Principal Statistician

Sciris Group Ltd
London
About Source

Source is a HEOR market access consultancy specialising in health economics, systematic review and health technology assessment. At Source, we have a supportive and friendly team who are focused on delivering high-quality evidence-based solutions for their clients. We are proud to be part of a wider, commercialisation network - SCIRIS.

About SCIRIS:

Employing over 300 people in the UK and North America across seven offices, with headquarters in London, UK, SCIRIS connects best-in-class capabilities to achieve success across therapeutic categories and all phases of brand development, offering bespoke programmes in healthcare communications, creative and brand strategy, medical compliance, and insights.

Job Description

We are looking for an experienced statistician who has an interest in applied statistical methods for evidence synthesis. We are looking for an enthusiastic and motivated individual who is proactive, shows initiative, and has experience in contributing to the design and execution of statistical analyses, reporting results and mentoring fellow statisticians. The role will be based in either Oxford, London or home-based. We are open to a fully remote hire and would expect hybrid workers to be in the office two days a week.

Duties will include:
  • Leading on statistical projects, including:
    • Meta-analysis feasibility assessments and statistical analysis plans (SAP)
    • Writing code to perform analyses including pair-wise meta-analyses, network meta-analyses (NMA), population-adjusted indirect comparisons, and individual patient data (IPD) analysis
  • Undertaking project management activities on statistical projects to ensure quality and timely delivery including:
    • Project planning
    • Client liaison
    • Managing and reviewing the work of other statisticians
    • Quality control
  • Leading on the development of evidence synthesis proposals and pitch presentations
  • Leading on the development of standard operating and quality control processes for evidence synthesis
  • Delivering training to statisticians, health economists, and systematic reviewers
  • Line management of small team of statisticians
Skills, Knowledge & Experience Required:

ESSENTIAL:

Education
  • Educated to an advanced level: Master's degree or above in quantitative discipline.
Experience
  • Previous HEOR industry experience.
  • Previous experience with statistical analyses for HTA submission.
  • Substantial experience in evidence synthesis techniques, including meta-analysis, NMA (including time-varying survival analyses), population-adjusted indirect comparisons.
  • Proficiency with statistical software.
  • Extensive experience of generating feasibility assessments, SAPs and technical reports.
  • Presentation of complex statistical information and results clearly to colleagues and clients with a wide range of statistical understanding.
  • Strong understanding of how meta-analysis / ITC results inform health economic models.
Leadership and Mentoring
  • Some experience in technical and statistical leadership of teams, mentoring junior statisticians, and fostering a learning environment.
General Skills
  • Good communicator and influencer at all levels of the organisation, with the ability to impart knowledge clearly on a particular subject area(s).
  • Excellent level of accuracy and attention to detail.
  • Self-management skills with a focus on results for timely and accurate completion of competing deliverables.
  • Strong problem-solving ability.
  • Ability to work independently and as part of a team.
DESIRABLE:

Education
  • Master's degree or above in medical statistics.
Experience
  • Experience with recent NMA developments such as ML-NMR methodology.
  • Experience with R, Stata and / or WinBUGS/OpenBUGS specifically.
  • Provide expert input when reviewing reports written by statistics colleagues and content from other teams, to ensure the reports meet a high standard and align with company house-style.
  • Experience in contributing to the continuous learning and upskilling of more junior members of the statistics team.
  • Experience of selling and providing training sessions to external clients.
  • Innovative solutions for complex problems.
Leadership and Mentoring
  • Substantial experience in technical and statistical leadership of teams, mentoring junior statisticians, and fostering a learning environment.
General Skills
  • Identify risks to project delivery and/or quality, lead in a way to minimise risks.
What to expect:

Join a company where balance, growth, and excellence guide everything we do.
  • A genuinely friendly and supportive environment where you can thrive both personally and professionally, within a consultancy that truly values its people and the quality of its client work.
  • Accessible and approachable leadership, offering regular interaction with senior team members who are committed to your development and helping you build the skills needed to advance your career.
  • Diverse and rewarding project exposure, giving you the opportunity to collaborate with a wide range of clients and teams, and apply varied methods while contributing to impactful work with major pharmaceutical companies.
  • Empowerment to take ownership of your role, with the freedom to grow your expertise, shape your career path, and make meaningful contributions from day one.
The Package:

Competitive salary and benefits package.
Posted 2025-10-15

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