Research Assistant in RNA Delivery
CHEManager International
London
About Us About the Faculty The Faculty of Life Science & Medicine at King's College London is one of Europe's largest centres for biomedical research and teaching. The School's academic expertise is globally acclaimed in a wide range of basic and applied sciences, continuing a rich legacy of pioneering King's scientists. Many of the research groups were top rated in the last HEFCE Research Assessment Exercise. The Faculty's students enjoy unrivalled learning opportunities, supported by strong partnerships with industry and healthcare organisations. At both undergraduate and postgraduate level, students benefit from the School's first-class facilities and those of its partners, including the world-renowned partner NHS Trusts. As the academic partner of choice for some of the world's leading businesses the Faculty of Life Science & Medicine is shaping the future of healthcare through its membership of the government's Global Medical Excellence Cluster and its award-winning spin out companies. The Faculty is based at the Guy's (London Bridge) and Waterloo Campuses. The two campuses are located in close proximity to each other on the vibrant South Bank. The facilities for teaching and research at the Guy's and Waterloo Campuses have been greatly enhanced since 1998 through a capital investment programme of approximately £200 million, which has provided state-of-the-art laboratories and a high-quality learning environment. Within the Faculty, research divisions provide the focus for the organisation of research activity while teaching is delivered by discipline-based departments. The Waterloo Campus provides the home for the Institute of Pharmaceutical Science, the Analytical and Environmental Sciences Division, the Diabetes and Nutritional Sciences Division, and the Vascular Biology section of the Cardiovascular Division. Some aspects of the Institute of Pharmaceutical Science activity are located on the Guy's Campus. Teaching is organised by the Departments of Pharmacy & Forensic Science, Nutrition and Dietetics. Specialist facilities include SRIF-funded Genomics and Mass Spectrometry centres, a radioisotope suite, cell culture facilities, a Biological Services Unit, a metabolic unit for human feeding studies and high-quality library and IT provision. There are excellent analytical facilities including ultracentrifuge, NMR spectroscopy, HPLC, GC, GC/NIMS, GC/EIMS, GC/MS-MS, LC/MS-MS, ICP-OES and ICP-mass spectrometry equipment (see also ). About The Institute Of Pharmaceutical Science From molecules to medicine The Institute of Pharmaceutical Science (IPS) is concerned with gaining a detailed understanding of the human pathological state and employing this knowledge to discover, design, develop and deliver drugs to the patient with a view to managing disease. It provides the multidisciplinary approach required to contribute to the overall development of pharmacologically active compounds from their earliest stages of conception at the bench through their presentation as medicines, to the analysis of their use within the community. IPS is one of the largest divisions in the health schools and is currently organised in five groups: Pharmaceutical Biophysics, Chemical Biology, Drug Delivery, Pharmacology and Therapeutics, and Clinical Practice and Medication Use. There is a vibrant PhD programme with more than 100 students, and a comprehensive suite of postgraduate taught programmes. In the Research Excellence Framework 2014, based on 'power', a factor taking into account the quality of the research output and the number of researchers assessed, King's College London was ranked first in the UK out of the 83 universities that made returns in Unit of Assessment 3, to which IPS contributed. The Institute of Pharmaceutical Science has strong links with many of the other research divisions at King's College London and consequently has developed a critically important central role in the total research effort of the College. Staff have a substantial number of collaborations at a local, national and international level. Following the accreditation of King's Health Partners, our Academic Health Sciences Centre, IPS joined three NHS trust pharmacy departments (Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts) and the Guys Drugs Research Unit to form the Pharmaceutical Sciences Clinical Academic Group. The aim is to cement the collaboration between staff in the Institute and the NHS Trusts and achieve excellence in service provision, research, and in education and training. About The Role The post-holder is expected to carry out pioneering laboratory work in engineering extracellular vesicles (EVs) to create novel delivery systems for oral delivery of mRNA. Experience in isolation and characterisation of EVs, together with intestinal epithelial cell culture is mandatory for the role. Furthermore, the candidate is expected to have strong skills and experience in nanomaterial characterisation and biological assays such as cytotoxicity testing and measurement of cell uptake of materials. The post holder is expected to participate in regular individual and group research meetings to communicate their research and receive feedback, in addition to attending external scientific meetings/conferences. Additionally, the post holder will be expected to engage in disseminating their research via publications and as such, they are expected to prepare manuscripts for publication. Finally, the post holder may be required to supervise undergraduate project students and will be expected to participate in regular lab management activities. This is a full-time role and you will be offered a fixed term contract until 31/12/2026. Research staff at King's are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers , applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information. About You To be successful in this role, we are looking for candidates to have the following skills and experience: Essential Criteria
- Degree in Pharmacy, Pharmaceutical Science, Biological Science, Chemical/Materials Science or similar
- Research experience in Extracellular Vesicles
- Research experience in nanomaterial characterisation
- Research experience in intestinal epithelial cell culture
- Excellent communication skills
- Research experience in nucleic acid delivery
- Research experience in milk-derived EVs
- Supervision of undergraduate students in research projects
Posted 2025-12-21
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