Associate Director, CMC Drug Substance
Your work will change lives. Including your own.
The Impact Youll Make
Recursion is on the cutting edge of drug discovery generating proprietary maps of biology that provide unique insights driving target identification validation and ultimately novel clinical candidates. We are seeking an Associate Director CMC Drug Substance to advance our current and future clinical assets through development and ultimately to patients in need.
In this role you will:
- Lead external drug substance development across our portfolio including oversight of CDMOs and strategic technical development relationships
- Provide technical leadership project management and oversight of drug substance process development and manufacturing activities supporting Recursions clinical programs
- Ensure delivery of drug substance from external manufacturing campaigns adhering to current quality guidelines and delivery timelines. Typical travel to external manufacturing sites is 10-20% of the time.
- Critically analyze process and analytical data to identify and resolve key synthetic challenges during drug substance development
- Participate in developing and extending our CDMO relationships budget planning and forecasting for drug substance expenditures and achieving our quality requirements
The Team Youll Join
As Associate Director CMC Drug Substance you will be an essential member of the Recursion CMC Team reporting to the Executive Director CMC Drug Substance. The CMC Team is an empowered execution-minded group of scientists and technical experts responsible for translating Recursions innovative science to patients in clinic through CMC activities and deliverables.
The Experience Youll Need
- Ph.D. in organic chemistry or closely related field with a minimum of 5-8 years experience or M.S. with 8-12 years of experience
- Strong knowledge and experience in small molecule drug substance process development and manufacturing best practices across all phases of drug development from initial regulatory filings through registration validation and launch
- Prior experience leading external development and CDMO relationships is a plus
- Demonstration of cross-functional understanding related to drug substance development including salt/polymorph screening phase appropriate analytical development standard process of drug product development quality and regulatory affairs
- Well-versed in the latest trends impacting drug substance technology manufacturing and the outsourcing industry
Working Location & Compensation:
This is an office-based hybrid position at one of our offices in either Milton Park or London England . Employees are expected to work in the office at least 50% of the time.
At Recursion we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role the estimated current annual base range for this role is 84000 to 98900 (GBP) . You will also be eligible for an annual bonus and equity compensation as well as a comprehensive benefits package.
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The Values We Hope You Share:
- We act boldly with integrity. We are unconstrained in our thinking take calculated risks and push boundaries but never at the expense of ethics science or trust.
- We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up speaking honestly and taking action.
- We learn actively and adapt rapidly. Progress comes from doing. We experiment test and refine embracing iteration over perfection.
- We move with urgency because patients are waiting. Speed isnt about rushing but about moving the needle every day.
- We take ownership and accountability. Through ownership and accountability we enable trust and autonomyleaders take accountability for decisive action and teams own outcomes together.
- We are One Recursion. True cross-functional collaboration is about trust clarity humility and impact. Through sharing we can be greater than the sum of our individual capabilities.
Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate support one another spend our time make decisions and celebrate collectively.
More About Recursion
Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS a platform built across diverse technologies that continuously generate one of the worlds largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale up to millions of wet lab experiments weekly and massive computational scale owning and operating one of the most powerful supercomputers in the world Recursion is uniting technology biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City where it is a founding member of BioHive the Utah life sciences industry collective. Recursion also has offices in Toronto Montréal New York London Oxford area and the San Francisco Bay area. Learn more at or connect on X (formerly Twitter)and LinkedIn.
Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin age disability veteran status or any other characteristic protected under applicable federal state local or provincial human rights legislation.
Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursions internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
Required Experience:
Director
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